Vaccination
​Immunization Updates

HPV Vaccine Update

What has changed in the new HPV vaccine recommendations?

Dosing schedules have changed. The CDC now recommends two doses of HPV vaccine for people starting the vaccination series before the 15th birthday.


The CDC continues to recommend routine vaccination for girls and boys at age 11 or 12 years. The vaccination series can be started at age nine. The CDC also recommends vaccination through age 26 years for females and through age 21 years for males. Males age 22 – 26 years may be vaccinated.


What is the recommended two-dose HPV vaccination schedule?

For girls and boys starting the vaccination series before the 15th birthday, the recommended schedule is two doses of HPV vaccine. The second dose is given 6 – 12 months after the first dose (0, 6 –12 month schedule).


When is a 3-dose schedule required?

The CDC continues to recommend a three dose schedule for persons starting the HPV vaccination series on or after the 15th birthday and for persons with certain immunocompromising conditions. The second dose is given one to two months after the first dose, and the third dose is given six months after the first dose (0, 1 – 2, 6 month schedule).

Recommended Immunization Schedule Update

In October 2016, the Advisory Committee on Immunization Practices (ACIP) voted to approve the following recommended immunization schedules: Children and Adolescents Aged 18 Years or Younger and the Adult Immunization Schedule for Adults Aged 19 Years or Older

The following links contain information regarding the changes and updates to the new schedules –


The new immunization schedules can be viewed on the CDC website.

Zoster Vaccine at Age 60+ Provides Highest Protection

ZosterThe herpes zoster vaccine is FDA-approved for patients aged 50 and older. However, the Advisory Committee on Immunization Practices (ACIP) recommends that adults aged 60 and older should receive the zoster vaccine. Unity follows the ACIP recommendation and provides coverage for the vaccine at age 60 and older. Please check your patient’s coverage before administering the vaccine. The risk of zoster re-activation increases significantly at ages 50-60 years with the highest risk in patients 80-89 years.2


Studies have shown that the zoster vaccine has the most benefit when given to patients aged 60-69 years and the least benefit when given to patients aged 70 and older .3 Zoster protection and reduction in symptom severity decreases over time. Therefore administration of the vaccine in patients age 60 and older allows for the highest protection at the time of highest risk.2,3  Unity covers the zoster vaccine in patients aged 60 and older.


Patients on the antiviral medications: acyclovir (Zovirax), famciclovir (Famvir), and valacyclovir (Valtrex) should stop their medication at least 24 hours before receiving the zoster vaccine. These medications interfere with herpes virus replication and should not be restarted for at least 14 days to ensure an adequate response to the vaccine.1

References:

  1. Advisory Committee on Immunization Practices. General recommendations on immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP). https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6002a1.htm. Published January 2011. Accessed February 20, 2017.
  2. Advisory Committee on Immunization Practices. Prevention of Herpes Zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP). https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5705a1.htm. Published June 2008. Accessed February 20, 2017.
  3. Levin MJ, Oxman MN, Zhang JH, et al. Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine. J Infect Dis. 2008;197(6): 825-835.